Institute for Pathology "Victor Babes" 1 article published in JoVE Medicine Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access Anne Cornelissen*1, Roberta Florescu*1, Nicole Schaaps1, Mamdouh Afify1, Sakine Simsekyilmaz1, Elisa Liehn*1,2,3, Felix Vogt*1 1Division of Cardiology, Angiology, and Critical Care, University Hospital RWTH Aachen, 2Department for Operative Intensive Medicine, University Hospital RWTH Aachen, 3Institute for Pathology "Victor Babes" This protocol describes the implantation of human coronary stents into the abdominal aorta of rats with an apoE-/- background using a trans-femoral access. Compared with other animal models, murine models carry the advantages of high throughput, reproducibility, ease of handling and housing, and a broad availability of molecular markers.
